How to Make It
To prepare frosting, place goji berries and 1/3 cup warm water in a small bowl. Let stand 20 minutes.
Place goji berry mixture in a blender; process until smooth. Pour mixture through fine-mesh strainer; discard seeds. Set aside.
Place cream cheese and 1/2 cup yogurt in the bowl of a stand mixer. Beat on high until smooth. Add powdered sugar; beat on low until combined. Add goji mixture; beat on medium until combined. Chill 30 minutes.
To prepare cupcakes, preheat oven to 350°F. Line 12 muffin cups with liners; coat with baking spray. Place sesame seeds in a mini food processor; process until seeds form a paste. Place in a bowl. Whisk in eggs, granulated sugar, 1/2 cup yogurt, milk, oil, and vanilla.
Whisk flour, cocoa, baking powder, baking soda, and salt in a medium bowl. Add sesame seed mixture to flour mixture; whisk to combine.
Divide batter among prepared muffin cups. Bake at 350°F for 17 to 19 minutes or until a wooden pick inserted in center comes out clean. Cool in pan on a wire rack for 10 minutes. Remove cupcakes from pan; cool completely on wire rack. Spread frosting evenly on cupcakes, and garnish with black sesame seeds.
SNEAKY SUBSTITUTION: We skipped the artificial food dyes and instead used red-orange goji berries to achieve naturally colored frosting. Goji berries are packed with eye-healthy vitamin A and can be found at most well-stocked supermarkets in the dried fruit or bulk bin section.